Maleimide-PEG4-NHS Ester

Maleimide-PEG4-NHS Ester - Names and Identifiers

Name	Maleimide-PEG4-NHS Ester
Synonyms	Mal-PEG4-NHS Maleimide-PEG4-NHS Ester alpha-MaleiMidopropionyl-oMega-succiniMidyl-4(ethylene glycol) O-[N-(3-MaleiMidopropionyl)aMinoethyl]-O′-[3-(N-succiniMidyloxy)-3-oxopropyl]triethylene glycol N-[15-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl]-2,5-dihydro-2,5-dioxo-1H-pyrrole-1-propanamide
CAS	756525-99-2
EINECS	201-258-5

Maleimide-PEG4-NHS Ester - Physico-chemical Properties

Molecular Formula	C22H31N3O11
Molar Mass	513.5
Density	1.36±0.1 g/cm3(Predicted)
pKa	15.01±0.46(Predicted)
Storage Condition	-20°C
MDL	MFCD11041113

Maleimide-PEG4-NHS Ester - Risk and Safety

WGK Germany

Maleimide-PEG4-NHS Ester - Upstream Downstream Industry

Raw Materials

Mal-Amido-PEG4-acid
BOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID
3-Maleimidopropionic acid
N-Succinimidyl 3-maleimidopropionate
N-Hydroxysuccinimide

Maleimide-PEG4-NHS Ester - Introduction

Maleimide-PEG4-NHS Ester(Maleimide-PEG4-NHS Ester) is a compound whose chemical structure contains Maleimide,PEG4 (polyethylene glycol tetraol) and NHS Ester components.

Properties of the compound include:
-Appearance: Usually a white to light yellow solid.
-Solubility: Soluble in organic solvents, such as dimethyl sulfoxide (DMSO) and dimethylformamide (DMF).

The use of Maleimide-PEG4-NHS Ester is mainly in the fields of biochemistry and biomedicine, mainly used as a protein modifier for the preparation of biomolecules with specific chemical properties. It can be linked to proteins or peptides for applications in drug delivery, fluorescent probes and diagnostic reagents. Among them, the NHS Ester moiety reacts efficiently with amine groups and is often used to react with biomolecules containing amino acid residues.

The compound is usually produced by chemical synthesis. The specific preparation details may vary, but generally include attaching the NHS Ester activator to PEG4, followed by reaction with Maleimide to form the final Maleimide-PEG4-NHS Ester product.

Regarding safety information, the following should be noted when handling and storing compounds:
-The compound should be stored under dark conditions and away from high temperature or fire sources to avoid decomposition and dangerous accidents.
-During operation, Good Laboratory safety practices should be observed, including the wearing of personal protective equipment such as lab gloves and goggles.
-Avoid contact with skin, eyes and respiratory tract. If contact occurs, rinse immediately with plenty of water and seek medical help.
-This compound may cause potential harm to the environment, so waste should be treated and disposed of in accordance with relevant environmental regulations.

Last Update：2024-04-09 20:49:11